Supplementary Figure 3: Area under the curve (AUC) distribution of kinase specificity models. | Nature Methods

Supplementary Figure 3: Area under the curve (AUC) distribution of kinase specificity models.

From: MIMP: predicting the impact of mutations on kinase-substrate phosphorylation

Supplementary Figure 3

(left) AUCs computed using kinase binding sites from all other kinase families as the negative set. AUCs below 0.6 (red line) were discarded from the analysis. (right) AUCs computed using a background of random unphosphorylated STY-centered sites. All retained models have AUCs greater than 0.64 (red line).

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