Supplementary Figure 5: Kinases with differential melting profiles observed in cell lysates treated with 100 µM (S)-crizotinib.
From: Proteome-wide drug and metabolite interaction mapping by thermal-stability profiling
Treatment of SW480 cell lysates with 100 µM (S)‑crizotinib leads to a stabilization of (a) PI3K-beta (PIK3CB) and (b) CDK2. Data indicate one technical replicate.
