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Stem cells

Fast track to neurons

New protocols generate neurons directly from fibroblasts using only chemical cocktails.

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References

  1. Li, X. et al. Small-molecule-driven direct reprogramming of mouse fibroblasts into functional neurons. Cell Stem Cell 17, 195–203 (2015).

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  2. Hu, W. et al. Direct conversion of normal and Alzheimer's disease human fibroblasts into neuronal cells by small molecules. Cell Stem Cell 17, 204–212 (2015).

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Nawy, T. Fast track to neurons. Nat Methods 12, 915 (2015). https://doi.org/10.1038/nmeth.3611

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