New protocols generate neurons directly from fibroblasts using only chemical cocktails.
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References
Li, X. et al. Small-molecule-driven direct reprogramming of mouse fibroblasts into functional neurons. Cell Stem Cell 17, 195–203 (2015).
Hu, W. et al. Direct conversion of normal and Alzheimer's disease human fibroblasts into neuronal cells by small molecules. Cell Stem Cell 17, 204–212 (2015).
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Nawy, T. Fast track to neurons. Nat Methods 12, 915 (2015). https://doi.org/10.1038/nmeth.3611
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DOI: https://doi.org/10.1038/nmeth.3611