Supplementary Figure 4: Array spots generated from diseased tissues.
From: Tissue matrix arrays for high-throughput screening and systems analysis of cell function
Diseased tissue arrays were fabricated by processing tissue taken from murine mammary tumors and skeletal muscle of mutant dystrophic mice. Tissue was processed similar to normal tissue and spotted in a microarray with normal tissue controls. Histological staining patterns with hematoxylin and eosin (H&E) and Masson’s trichrome are different for normal mammary, early stage tumor, and late stage tumor tissue. Increased blue staining with Masson’s trichrome indicates higher levels of collagen content (n = 3 array spots). Scale bar = 20 μm.
