Supplementary Figure 11: Correlation and volcano plots of the TRiC apo and ATP-AlFx datasets using different quantitative cross-linking workflows. | Nature Methods

Supplementary Figure 11: Correlation and volcano plots of the TRiC apo and ATP-AlFx datasets using different quantitative cross-linking workflows.

From: xTract: software for characterizing conformational changes of protein complexes by quantitative cross-linking mass spectrometry

Supplementary Figure 11

(a) Correlation of common data points between the LFQ-like workflow and the differential isotopic label workflow. (b) Volcano plot of the LFQ-like workflow. (c) Volcano plot of the differential isotopic label workflow. In the volcano plots the log2 ratios are plotted against the adjusted negative log10 P values. Indicated by color is if the observed changes are significant (blue) or not (red) (adjusted P value < 0.01 and absolute log2 fold change >1). The log2 ratios are shown with the apo experiment used as reference.

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