Supplementary Figure 10: Orientation of divisions at the transition from 8- to 16-cell stage is not random.
From: Inverted light-sheet microscope for imaging mouse pre-implantation development
Distribution of division angles (Online Methods) during cell divisions from 2-cell stage up to 32-cell stage. Mitoses where cells divided parallel to the embryo surface have an angle of division 0°, whereas mitoses where cells divided in the direction of the inside/outside axis have a division angle of 90°. Random distribution is indicated by a black line. Probabilities that observed angles are coming from this random distribution are shown inside the graphs (Kolmogorov–Smirnov test, sample size inside graphs).
