Supplementary Figure 3: Change in secondary structure for optilib oligos. | Nature Methods

Supplementary Figure 3: Change in secondary structure for optilib oligos.

From: Predictable tuning of protein expression in bacteria

Supplementary Figure 3

(a) Change in secondary structure for the transcripts of all the 40,526 targetting E. coli genes. The average change is 0.51 kcal/mol. * denotes previously observed changes in free energy that led to a significant change in expression levels19. (b) Distribution of oligos with 1-6 nucleotides changed from the wild-type in optilib.

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