Supplementary Figure 8: Analysis of human 20S proteasome complex.
From: An informatic framework for decoding protein complexes by top-down mass spectrometry
The 3-tier tandem mass spectrometric data for the proteasome is illustrated with (a) MS1, (b) MS2 data and (c) the graphical fragment maps of four ejected monomer corresponding to subunits beta-6, alpha-4, alpha-5 (co-isolated with alpha-4), and alpha-7; E-values and C-scores from step 2 of the search framework are shown. (d) The highest MPC-scores associated with searches of each subunit. The isoform information and stoichiometry of these results is shown in Supplementary Table 4.
