Supplementary Figure 2: Detailed definitions of some terms used in Supplementary Note 1 and Supplementary Figure 1. | Nature Methods

Supplementary Figure 2: Detailed definitions of some terms used in Supplementary Note 1 and Supplementary Figure 1.

From: Integrative genomic analysis by interoperation of bioinformatics tools in GenomeSpace

Supplementary Figure 2

Stemness signature: a set of genes which are upregulated in induced cancer stem cells (iCSCs), and enriched in embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs). These genes represent a stem cell state. Non-stemness signature: a set of genes which are upregulated in iCSCs, but are not associated with the stemness signature. Stemness “ON”: a set of breast cancer tumor samples which have significant enrichment in the stemness signature. Stemness “OFF”: a set of breast cancer tumor samples which do not have enrichment of the stemness signature.

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