Supplementary Figure 2: Differential expression analysis using MAST on mESC inDrop data
From: Diffusion pseudotime robustly reconstructs lineage branching
Log-fold change (lfc) analysis of the DPT inferred ‘decision’ group vs. all other groups (a,c,e) and head fold cells vs. primitive streak and 4SG- cells (d, e). The displayed genes were filtered for an lfc > 1 and a Bonferroni-adjusted p-value< 0.01. Plots are ordered by absolute lfc between the states. a) Decision area (red) vs. Precursor area (blue), b) Head fold (red) vs. Primitive streak (blue), c) Decision area (red) vs. branch 2 end point (blue), d) Head fold (red) vs. 4SG negative cells (blue), e) Decision area (red) vs. branch 1 end point (blue).
