Supplementary Figure 6: ENTH/VHS domains can simultaneously associate with membranes, M6PR-tail and ubiquitin.
From: A bacterial genetic selection system for ubiquitylation cascade discovery
Superimposing the ENTH complex with the lipid phosphatidylinositol-4,5-bisphosphate, GGA3-VHS complex with the Mannose-6P Receptor tail and the STAM1-VHS:Ub shows that membrane and Ub associations occur at opposite sides of the domain and therefore can occur simultaneously.
