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Genomics

RNA detection with C2c2

Nature Methods volume 13, page 905 (2016)Cite this article

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The discovery of two distinct endonuclease activities in the C2c2 protein explains how template RNAs are processed in type VI CRISPR systems and enables the development of a sensitive RNA detection system.

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References

  1. East-Seletsky, A. et al. Two distinct RNase activities of CRISPR-C2c2 enable guide-RNA processing and RNA detection. Nature 538, 270–273 (2016).

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Authors
  1. Richard Pattison
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Pattison, R. RNA detection with C2c2. Nat Methods 13, 905 (2016). https://doi.org/10.1038/nmeth.4062

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