Supplementary Figure 4: Coverage of resources on various groups of proteins.
From: OmniPath: guidelines and gateway for literature-curated signaling pathway resources
Categories and shaded areas as on Supplementary Fig. 5. (a) Percentage of human receptors (as listed in HPMR) covered by pathway resources; (b) Percentage of transcription factors (TFs; from TF Census) covered by pathway resources; (c) Number of complexes (as defined in CORUM) and (d) number of post-translational modifications (PTMs) from PTM resources that can be mapped onto the network (i.e. corresponding group of proteins or interacting protein pair can be found). (e-f) Percentage of cancer driver genes (as listed in Cancer Gene Census and IntOGen) covered by pathway resources covered by pathway resources. (g) Percentage of disease related genes, as listed in DisGeNet, covered by pathway resources; (h) Number of all enzyme-substrate pairs by PTM resources, and number of the enzyme-substrate interactions for a corresponding edge can be found in any of the resources.
