Supplementary Figure 7: Comparison of four different TTTN sequences as potential PAMs. | Nature Methods

Supplementary Figure 7: Comparison of four different TTTN sequences as potential PAMs.

From: In vivo high-throughput profiling of CRISPR–Cpf1 activity

Supplementary Figure 7

Indel frequencies for four different TTTN sequences tested as potential PAMs for AsCpf1 (a) and LbCpf1 (b). Error bars represent s.e.m. *P < 0.05, **P < 0.01, ***P < 0.001, ANOVA followed by Tukey’s post hoc test. Number of tested guide sequences (n) = 11, 13, 12, 12 for AsCpf1 and 14, 13, 15, 10 for LbCpf1.

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