Supplementary Figure 8: Comparison of indel frequency rankings between AsCpf1 and SpCas9 using the same and reverse target sequences.
From: In vivo high-throughput profiling of CRISPR–Cpf1 activity
The relationship between indel frequency rankings of SpCas9 target sequences and those of Cpf1 targeting the same (left) or reverse (right) sequences. The sequences that are marked with a red color, 5’-GGG-3’ and 5’-TTTA-3’, were used as the PAMs for SpCas9 and AsCpf1 target sequences, respectively. The known activity rank for the SpCas9 target sequence (ref. 14) is used for comparison.
