Supplementary Figure 7: XES data processing.
From: Drop-on-demand sample delivery for studying biocatalysts in action at X-ray free-electron lasers

a. Raw image (minus outlier pixels), with wide ROI shown in red. b. Smooth polynomial background fit to data outside the wide ROI and extrapolated into the ROI (intensified by 4x for illustrative purposes). c. Integration of the wide ROI for both the raw and background. d. Corrected image with tight ROI based on Gaussian fit. e. Final corrected spectrum.