Supplementary Figure 2: The false discovery rate (FDR) vs. sensitivity of detecting differentially expressed transcripts on Polyester simulated data
From: Salmon provides fast and bias-aware quantification of transcript expression
The false discovery rate (FDR) vs. the sensitivity of Salmon, Salmon (align), kallisto and eXpress on Polyester simulated RNA-seq data using empirically-derived fragment GC bias profiles. All methods were run with bias-correction enabled, but only Salmon’s model incorporates corrections for fragment GC bias. This leads to a large improvement in sensitivity at almost every FDR value.
