Supplementary Figure 3: Trace plots from Bayesian models of degradation.
From: Power analysis of single-cell RNA-sequencing experiments
The posterior samples from the model parameters in Stan41 for both the ERCC and SIRV analysis show very narrow confidence intervals and good correspondence between the different sampling chains. The SIRV based model is slightly noisier, which can be expected, as isoform-level expression when multiple isoforms are present is a harder quantification problem than quantifying expression of the unique ERCC sequences. For the ERCC model, the mode of the degradation rate parameter p is 19%, and for the SIRV model it is 18.5%.
