Supplementary Figure 10: Comparison of the RRM2-EMCV^F models derived from NMR and CLIR-MS/MS.

RRM2 recognizes EMCV^F by contacting C358 and U359 in pocket 1 and 2 by base-specific hydrogen bonds in both, a, NMR and, b, CLIR-MS/MS derived models. While U360 does not contact RRM2, U361 stacks on Tyr 267.