Supplementary Figure 2: Transcription factor combination AMD induces the differentiation of human pluripotent stem cells into a homogenous population of GABAergic neurons with high yield and reproducibility.
From: Generation of pure GABAergic neurons by transcription factor programming
(a) Representative traces of sIPSCs recorded from AMD-iN cells generated from three different human pluripotent stem cell lines. (b) AMD-iN cells generated from different cell lines show similar intrinsic properties in terms of membrane capacitance (Cm, bi), input-resistance (Rm, bii), and the average amplitude and frequency of the sIPSCs (biii and biv, respectively). Data are presented as mean ± SEM (one-way ANOVA, p > 0.05, n = 18 cells/condition), and filled circles represent values measured from individual cells.
