Figure 3: Diversity of feature distributions in morphological profiling.

(a–h) Morphological features display various types of distributions, including normal (a), skewed (b,c), uniform (d), multimodal (e–g), and even discrete distributions (h). The ranges in which features are represented also vary considerably. These histograms were obtained with feature values from a sample of 10,000 cells in the BBBC021 data set¹⁰⁸. The names of features correspond to conventions used in the CellProfiler software. The x axes show feature values (in different units), and the y axes show frequencies (cell counts).