Supplementary Figure 14: chromVAR identifies TF motifs associated with chromatin accessibility variation between macrophages resident in different tissues.
From: chromVAR: inferring transcription-factor-associated accessibility from single-cell epigenomic data
ATAC-seq data from Lavin et al. Sample labels for macrophages are based on the tissue of origin, while Monocytes and Neutrophils are labelled based on their cell type. a) Bias corrected deviations for variable TFs using data down-sampled to approximately 10,000 fragments per sample, b) Bias corrected deviations for variable TFs using full data. For both panels, TFs were chosen based on the variability using the down-sample data, with highly correlated motifs omitted. The row and column ordering were based on clustering of the motifs and samples using the down-sampled data.
