Supplementary Figure 12: Global relationships between transcriptional output, mRNA stability, and steady-state gene expression in mESCs as determined by SLAMseq.
From: Thiol-linked alkylation of RNA to assess expression dynamics
(a) Correlation between the rate of transcriptional output (Trx. Output) and steady-state abundance for 6442 genes in mESCs. Spearman correlation coefficient (r) and associated p-Value are indicated. (b) Correlation between half-life and steady-state abundance for 6442 genes in mESCs. Spearman correlation coefficient (r) and associated p-Value are indicated. (c) Correlation between half-life and the rate of transcriptional output for 6442 genes in mESCs. Spearman correlation coefficient is indicated. (d) Correlation between the rate of transcriptional output and the rate of RNA decay for 6442 genes in mESCs. Pearson’s correlation coefficient and associated p-Value are indicated.
