A technique combining mass spectrometry and infrared spectroscopy shows promise for unambiguous sequencing of linear oligosaccharides.
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References
Schindler, B. et al. Anomeric memory of the glycosidic bond upon fragmentation and its consequences for carbohydrate sequencing. Nat. Commun. 8, 973 (2017).10.1038/s41467-017-01179-y
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Doerr, A. Sequencing for carbohydrates. Nat Methods 14, 1126 (2017). https://doi.org/10.1038/nmeth.4528
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DOI: https://doi.org/10.1038/nmeth.4528
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