Supplementary Figure 9: Application of cellAlign on mouse and human preimplantation trajectories can be used to discriminate between genes with distinct dynamics rates in both species. | Nature Methods

Supplementary Figure 9: Application of cellAlign on mouse and human preimplantation trajectories can be used to discriminate between genes with distinct dynamics rates in both species.

From: Alignment of single-cell trajectories to compare cellular expression dynamics

Supplementary Figure 9

(a-b) Scaled expression (z-scores) of genes assigned to embryonic (a) and maternal (b) clusters across human developmental stages. (c) Scatterplot of the ordering of genes by their upregulation timing along human (x-axis) and mouse (y-axis) trajectories, showing high conservation of temporal regulation (n=288 genes, r = 0.18, linear regression p-value = 0.00173), yet marked differential regulation for a subset of genes. Color denotes point density.

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