Supplementary Figure 11: Rejected and confirmed novel HCMV ORFs.
From: Improved Ribo-seq enables identification of cryptic translation events
(a) Many of the novel ORFs from the HCMV re-annotation (see Fig. 2 in the main text) were filtered by PRICE due to too much noise off-frame, too many inactive codons, noise down- or upstream, no clear start codon, abortive translation or due to very weak expression. (b) In comparison to the 168 ORFs of the reference annotation and the 248 confirmed ORFs, about half of our novel ORFs were expressed at very low levels and thus might reflect not experimental but translational noise.
