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microRNA profiling on automated biochip platform reveals biomarker signatures from blood samples

Nature Methods volume 7, page 162 (2010)Cite this article

Abstract

febit's microfluidic microarray technology offers a promising approach for diagnostic testing based on automated microRNA (miRNA) biomarker profiling. The Geniom RT Analyzer makes it possible to measure expression of multiple miRNAs from limited clinical sample material, such as blood or other body fluids, formalin-fixed paraffin-embedded (FFPE) samples or fresh or frozen tissue. These specific miRNA profiles can serve as predictive biomarker signatures for the detection and classification of human diseases such as cancer.

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Figure 1
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Figure 3: Classification of multiple sclerosis (MS) patients based on miRNA biomarker signature data collected using the Geniom Biochip.

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Acknowledgements

We would like to thank J. Hoheisel and E. Meese for the studies performed in collaboration with their labs, and for their significant contribution in the establishment of the presented technology for biomarker profiling in patient samples.

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Authors and Affiliations

  1. febit biomed GmbH, Heidelberg, Germany

    Julia Lange

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  1. Julia Lange
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Correspondence to Julia Lange.

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This article was submitted to Nature Methods by a commercial organization and has not been peer reviewed. Nature Methods takes no responsibility for the accuracy or otherwise of the information provided.

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Lange, J. microRNA profiling on automated biochip platform reveals biomarker signatures from blood samples. Nat Methods 7, 162 (2010). https://doi.org/10.1038/nmeth.f.281x

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