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Capture Compounds for the functional isolation of nucleotide interacting proteins

Nature Methods volume 7, pages iii–iv (2010)Cite this article

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Abstract

The innovative Capture Compound mass spectrometry (CCMS) technology allows the functional reduction of biological sample complexity. Small synthetic molecules (Capture Compounds™) are used to interrogate native and even transmembrane proteins. Using nucleotide derivates as bait molecules allows discovery, isolation and profiling of interacting proteins from complex biological samples. Nucleotide-derived Capture Compounds are available as ready-to-use caproKits™ for proteomic research.

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Figure 1: Classification of captured proteins from HepG2 cell lysate using cAMP Capture Compounds, based on their biological process properties.
Figure 2

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Authors and Affiliations

  1. caprotec bioanalytics GmbH, Berlin, Germany

    Erik Dülsner, Christian Jurinke & Hubert Köster

Authors
  1. Erik Dülsner
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  2. Christian Jurinke
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  3. Hubert Köster
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Corresponding authors

Correspondence to Erik Dülsner or Christian Jurinke.

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This article was submitted to Nature Methods by a commercial organization and has not been peer reviewed. Nature Methods takes no responsibility for the accuracy or otherwise of the information provided.

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Dülsner, E., Jurinke, C. & Köster, H. Capture Compounds for the functional isolation of nucleotide interacting proteins. Nat Methods 7, iii–iv (2010). https://doi.org/10.1038/nmeth.f.312

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