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Caught in action

Nature Methods volume 7, page 12 (2010)Cite this article

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Screening reveals a chemical activator that triggers apoptosis by locking inactive but dynamic proenzymes into a more active state, suggesting a promising strategy for targeting proteases.

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References

  1. Wolan, D.W. et al. Small-molecule activators of a proenzyme. Science 326, 853–858 (2009).

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  1. Michael Eisenstein
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Eisenstein, M. Caught in action. Nat Methods 7, 12 (2010). https://doi.org/10.1038/nmeth0110-12

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  • DOI: https://doi.org/10.1038/nmeth0110-12

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