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Resetting the clock

Nature Methods volume 3, page 72 (2006)Cite this article

Abstract

By allowing a differentiated somatic nucleus to form metaphase chromosomes its chromatin is remodeled in a way that adapts its replication properties to the early embryonic context.

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Figure 1: When differentiated somatic nuclei are exposed to cell extract from mitotic oocytes, they replicate at a rapid rate.

References

  1. Lemaitre, J.M. et al. Mitotic remodeling of the replicon and chromosome structure. Cell 123, 787–801 (2005).

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Authors
  1. Nicole Rusk
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Rusk, N. Resetting the clock. Nat Methods 3, 72 (2006). https://doi.org/10.1038/nmeth0206-72a

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  • DOI: https://doi.org/10.1038/nmeth0206-72a

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