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Pinning the tail on the substrate

Abstract

Two high-throughput 'kinomic' analysis strategies could provide kinase researchers with a bounty of information about the targets and the regulation of their favorite enzymes.

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References

  1. Ptacek, J. et al. Global analysis of protein phosphorylation in yeast. Nature 438, 679–684 (2005).

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  2. Dephoure, N. et al. Combining chemical genetics and proteomics to identify protein kinase substrates. Proc. Natl. Acad. Sci. USA 102, 17940–17945 (2005).

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Eisenstein, M. Pinning the tail on the substrate. Nat Methods 3, 74 (2006). https://doi.org/10.1038/nmeth0206-74

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  • DOI: https://doi.org/10.1038/nmeth0206-74

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