Abstract
Two high-throughput 'kinomic' analysis strategies could provide kinase researchers with a bounty of information about the targets and the regulation of their favorite enzymes.
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References
Ptacek, J. et al. Global analysis of protein phosphorylation in yeast. Nature 438, 679–684 (2005).
Dephoure, N. et al. Combining chemical genetics and proteomics to identify protein kinase substrates. Proc. Natl. Acad. Sci. USA 102, 17940–17945 (2005).
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Eisenstein, M. Pinning the tail on the substrate. Nat Methods 3, 74 (2006). https://doi.org/10.1038/nmeth0206-74
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DOI: https://doi.org/10.1038/nmeth0206-74