Abstract
A surprisingly simple technique permits the rapid generation of submicrometer-sized vesicles from mammalian cells; these vesicles recreate the membrane and cytoplasmic environment of the parent cell, potentially enabling a broad range of nanoscale cellular screens.
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References
Pick, H. et al. Investigating cellular signaling reactions in single attoliter vesicles. J. Am. Chem. Soc. 127, 2908–2912 (2005).
Stamou, D. et al. Self-assembled microarrays of attoliter molecular vessels. Angew. Chem. Int. Ed. Engl. 42, 5580–5583 (2003).
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Eisenstein, M. Bubbles without toil or trouble. Nat Methods 2, 249 (2005). https://doi.org/10.1038/nmeth0405-249
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DOI: https://doi.org/10.1038/nmeth0405-249
