Abstract
By combining elements of protein engineering and directed evolution, researchers open the door to creating enzymes with diverse catalytic functions in a protein scaffold of their choice.
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References
Park, HS. et al. Design and evolution of new catalytic activity with an existing protein scaffold. Science 311, 535–538 (2006).
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Rusk, N. Improving evolution. Nat Methods 3, 242 (2006). https://doi.org/10.1038/nmeth0406-242
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DOI: https://doi.org/10.1038/nmeth0406-242