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Kinase chemical genomics—a new rule for the exceptions

An innovative genetic screen yields new insights into kinase active site structure, expanding the number of enzymes from this family addressable with chemical tools.

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Figure 1: Extension of the chemical genetic analysis of kinase activity to a larger part of the kinome.

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Cravatt, B. Kinase chemical genomics—a new rule for the exceptions. Nat Methods 2, 411–412 (2005). https://doi.org/10.1038/nmeth0605-411

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