Abstract
An improvement on the traditional method of polysome profiling, ribosome density mapping (RDM) can provide information about the distribution of ribosomes on individual mRNAs.
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References
Arava, Y. et al. Genome-wide analysis of mRNA translation profiles in Saccharomyces cerevisiae. Proc. Natl. Acad. Sci. USA 100, 3889–3894 (2003).
Arava, Y., Boas, F.E., Brown, P.O. & Herschlag, D. Dissecting eukaryotic translation and its control by ribosome density mapping. Nucleic Acids Res. 33, 2421–2432 (2005).
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Kaganman, I. Dissecting polysomes. Nat Methods 2, 488 (2005). https://doi.org/10.1038/nmeth0705-488
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DOI: https://doi.org/10.1038/nmeth0705-488