Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Research Highlights
  • Published:

Home-grown HCV

Abstract

Three teams of researchers have developed cell culture systems for the modeling of hepatitis C viral infection and the subsequent generation of infectious virus particles—an important breakthrough in the study of this disease.

This is a preview of subscription content, access via your institution

Access options

Buy this article

USD 39.95

Prices may be subject to local taxes which are calculated during checkout

Figure 1: Huh7.5.1 cells, five days after infection with JH1-derived HCV.

References

  1. Wakita, T. et al. Production of infectious hepatitis C virus in tissue culture from a cloned viral genome. Nat. Med. 11, 791–796 (2005).

    Article  CAS  Google Scholar 

  2. Zhong, J. et al. Robust hepatitis C virus infection in vitro. Proc. Natl. Acad. Sci. USA 102, 9294–9299 (2005).

    Article  CAS  Google Scholar 

  3. Lindenbach, B.D. et al. Complete replication of hepatitis C virus in cell culture. Science; published online 9 June, 2005.

Download references

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Eisenstein, M. Home-grown HCV. Nat Methods 2, 565 (2005). https://doi.org/10.1038/nmeth0805-565

Download citation

  • Issue date:

  • DOI: https://doi.org/10.1038/nmeth0805-565

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing