Abstract
UK researchers have devised a method of chromatin immunoprecipitation that requires as little as 100 cells, opening the door to epigenetics studies in primary cells and embryos.
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References
O'Neill L.P., VerMilyea M.D. & Turner B.M . Epigenetic characterization of the early embryo with a chromatin immunoprecipitation protocol applicable to small cell populations. Nat. Genet. 38, 835–841 (2006)
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Kiermer, V. Embryos and biopsies on the ChIP-ing forecast. Nat Methods 3, 583 (2006). https://doi.org/10.1038/nmeth0806-583
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DOI: https://doi.org/10.1038/nmeth0806-583
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