Single DNA molecules stretched in a nanochannel display melting patterns characteristic of their sequence.
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References
Reisner, W. et al. Single-molecule denaturation mapping of DNA in nanofluidic channels Proc. Natl. Acad. Sci. USA 107, 13294–13299 (2010).
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Rusk, N. Melting trapped DNA. Nat Methods 7, 678 (2010). https://doi.org/10.1038/nmeth0910-678
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DOI: https://doi.org/10.1038/nmeth0910-678