Abstract
A team from Harvard University has demonstrated that human embryonic stem cells have the capacity to reprogram an adult cell nucleus, leading to a new way of deriving human embryonic stem cell lines without using oocytes.
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References
Hwang, W.S. et al. Patient-specific embryonic stem cells derived from human SCNT blastocysts. Science 308, 1777–1783 (2005).
Cowan, C.A. et al. Nuclear reprogramming of somatic cells after fusion with human embryonic stem cells. Science 309, 1369–1373 (2005).
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Kiermer, V. Hot fusion. Nat Methods 2, 730 (2005). https://doi.org/10.1038/nmeth1005-730a
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DOI: https://doi.org/10.1038/nmeth1005-730a