Abstract
The Genetix ClonePix FL is a powerful way to find and collect antigen-specific clones from hybridoma fusions in a rapid one-step process—shortening the process timeline and allowing parallel interrogation of multiple antigens in the monoclonal antibody discovery process. ClonePix FL automatically screens the entire hybridoma fusion in situ and isolates only antigen-specific clones with the desired immunoglobulin isotype. If the fusion has many antigen-positive clones, then ClonePix FL can selectively collect only the best secretors.
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References
Davis, J.M., Pennington, J.E., Kubler, A.M. & Conscience, J.F. A simple, single-step technique for selecting and cloning hybridomas for the production of monoclonal antibodies. J. Immunol. Methods 50, 161–171 (1982).
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This article was submitted to Nature Methods by a commercial organization and has not been peer reviewed. Nature Methods takes no responsibility for the accuracy or otherwise of the information provided.
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Mann, C. Rapid isolation of antigen-specific clones from hybridoma fusions. Nat Methods 4, i–ii (2007). https://doi.org/10.1038/nmeth1028
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DOI: https://doi.org/10.1038/nmeth1028
