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Advancing forensics with precise target excision: the CellCut Plus laser microdissection instrument

Abstract

Laser microdissection instruments, such as the CellCut Plus® and SmartCut Plus® from Olympus, have proven to be excellent research and forensic tools. This is because they provide precise extraction of biological targets such as cells and cell components from standard slide preparations, dried samples and even cell cultures, making them perfect for even the most difficult isolations. In combination with new fluorescent markers, the CellCut Plus and SmartCut Plus become even more powerful and can yield forensic data that can lead to prosecutions that were not previously possible.

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Figure 1: Cells from a vaginal smear.
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References

  1. Elliot, K., Hill, D.S., Lambert, C., Burroughes, T.R. & Gill, P. Use of laser microdissection greatly improves the recovery of DNA from sperm on microscope slides. Forensic Sci. Int. 137, 28–36 (2003).

    Article  Google Scholar 

  2. Anslinger, K., Bayer, B., Mack, B. & Eisenmenger, W. Sex-specific fluorescent labelling of cells for laser microdissection and DNA profiling. Int. J. Legal Med. 121, 54–56 (2007).

    Article  CAS  Google Scholar 

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Acknowledgements

We acknowledge the assistance of K. Anslinger in the development of this manuscript.

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Correspondence to Joachim Kirschner.

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This article was submitted to Nature Methods by a commercial organization and has not been peer reviewed. Nature Methods takes no responsibility for the accuracy or otherwise of the information provided.

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Kirschner, J., Plaschke-Schluetter, A. Advancing forensics with precise target excision: the CellCut Plus laser microdissection instrument. Nat Methods 4, iii–iv (2007). https://doi.org/10.1038/nmeth1095

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