Abstract
Working from opposite ends of the protein folding problem, two research teams have developed powerful mathematical strategies that offer the potential to greatly clarify the relationship between primary sequence and native structure.
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References
Bradley, P. et al. Toward high-resolution de novo structure prediction for small proteins. Science 309, 1868–1871 (2005).
Socolich, M. et al. Evolutionary information for specifying a protein fold. Nature 437, 512–518 (2005).
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Doerr, A. Tackling biology's big question. Nat Methods 2, 803 (2005). https://doi.org/10.1038/nmeth1105-803
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DOI: https://doi.org/10.1038/nmeth1105-803