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Uncovering hidden relationships

Abstract

Two new studies tackle the complexities of synthetic genetic interaction—identifying relationships between gene products that interact functionally rather than physically.

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References

  1. Davierwala, A.P. et al. The synthetic genetic interaction spectrum of essential genes. Nat. Genet. 37, 1147–1152 (2005).

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  2. Measday, V. et al. Systematic yeast synthetic lethal and synthetic dosage lethal screens identify genes required for chromosome segregation. Proc. Natl. Acad. Sci. USA 102, 13956–13961 (2005).

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Eisenstein, M. Uncovering hidden relationships. Nat Methods 2, 806 (2005). https://doi.org/10.1038/nmeth1105-806

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  • DOI: https://doi.org/10.1038/nmeth1105-806

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