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Hybridization chain reaction

Nature Methods volume 1, page 186 (2004)Cite this article

Abstract

A new technique, based on a chain reaction of recognition and hybridization events between two sets of DNA hairpin molecules, offers an enzyme-free alternative for the rapid detection of specific DNA sequences.

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Figure 1: Schematic of the basic hybridization chain reaction.

RESEARCH PAPERS

  1. Dirks, R.M. & Pierce, N.A. Triggered amplification by hybridization chain reaction. Proc. Natl. Acad. Sci. USA 101, 15275–15278 (2004).

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Authors
  1. Daniel Evanko
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Evanko, D. Hybridization chain reaction. Nat Methods 1, 186 (2004). https://doi.org/10.1038/nmeth1204-186a

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  • DOI: https://doi.org/10.1038/nmeth1204-186a

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