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Fast and reliable MALDI-TOF MS–based microorganism identification

Abstract

Matrix-assisted laser desorption/ionization–time of flight mass spectrometry (MALDI-TOF MS) fingerprinting is a fast and reliable method for the classification and identification of microorganisms, with applications in clinical diagnostics, environmental and taxonomical research, or food-processing quality control. The BioTyperTM MALDI-TOF MS fingerprinting system allows researchers to perform this process for the unambiguous identification of bacteria, yeasts and fungi in minutes.

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Figure 2: BioTyper identification results.
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References

  1. Ryzhov, V. & Fenselau, C. Characterization of the protein subset desorbed by MALDI from whole bacterial cells. Anal. Chem. 73, 746–750 (2001).

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Correspondence to Markus Kostrzewa.

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This article was submitted to Nature Methods by a commercial organization and has not been peer reviewed. Nature Methods takes no responsibility for the accuracy or otherwise of the information provided.

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Maier, T., Klepel, S., Renner, U. et al. Fast and reliable MALDI-TOF MS–based microorganism identification. Nat Methods 3, i–ii (2006). https://doi.org/10.1038/nmeth870

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