Abstract
The use of Sartorius membrane adsorbers incorporated in AdenoPACK units facilitates and speeds up the purification step for adenovirus preparation, which can take days using traditional methods. Ready-to-use kits are available for processing cell culture volumes from 20 ml to 500 ml, permitting preparation of up to 3 × 1013 purified viral particles in only 2 hours. Plus, the method can be scaled up for adenovirus purification in process scale.
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References
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Delmdahl, N. Fast, effective and safe adenovirus purification with Vivapure AdenoPACK kits. Nat Methods 3, 658 (2006). https://doi.org/10.1038/nmeth909
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DOI: https://doi.org/10.1038/nmeth909
