Abstract
The Toponome Imaging System (TIS) is the latest development in automated multidimensional fluorescence microscopy. It is capable of imaging over 100 different molecular components in a single cell or tissue section at continuous intensity levels for the first time. TIS directly addresses protein-network architecture and function in healthy and diseased states—a completely new dimension in the life sciences.
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Bode, M., Krusche, A. Toponome Imaging System (TIS): imaging the proteome with functional resolution. Nat Methods 4, iii–iv (2007). https://doi.org/10.1038/nmeth998
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DOI: https://doi.org/10.1038/nmeth998
