Accurate estimates of disease burden are possible by building high-resolution geographical models. However, novel pathogens such as Zika virus pose substantial challenges, requiring both new analytical techniques and, where possible, serological surveys.
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Riley, S. Epidemiology: Making high-res Zika maps. Nat Microbiol 1, 16157 (2016). https://doi.org/10.1038/nmicrobiol.2016.157
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DOI: https://doi.org/10.1038/nmicrobiol.2016.157
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Asymptomatic Transmission and the Dynamics of Zika Infection
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