Figure 1: Overview of the cohort and framework for integrated analyses.
From: Integrated multi-omics of the human gut microbiome in a case study of familial type 1 diabetes
a, Pedigrees of participant families. Individuals who donated samples are represented by coloured symbols; these colours are reflected in all subsequent figures. Individuals with T1DM are represented by filled symbols. Samples of the two individuals denoted in grey letters and represented by symbols with dashed lines (M01.5 and M03.1) were only subjected to metagenomic analyses. b, Schematic representation of the per-sample analysis workflow. Resulting data sets framed with coloured boxes were used for cross-sample comparisons.
