Supplementary Figure 2: Expression of COUP-TFII and Sp8 in the human fetal brain at GW15.
From: Subcortical origins of human and monkey neocortical interneurons
(a–h) COUP-TFII and Sp8 double-immunostaining was performed on GW15 human brain sections. Note expression of COUP-TFII in an increasing rostral-to-caudal gradient from dLGE to dCGE. The RMS contained massive Sp8+ cells and very few COUP-TFII+ cells suggesting that COUP-TFII+ cells in the dLGE/dCGE migrate mainly into the cortex. (i) COUP-TFII+ cells in the dCGE were mainly located in the SVZ; the majority of them did not express Ki67. (h) In the vCGE, COUP-TFII+ cells were in the VZ and SVZ; many of them expressed Ki67. LV, lateral ventricle; Sep, septum; St, striatum; Th, thalamus.
